Table 1.
Study | Age (years) | Gender | Site | Symptoms | PAS diastase-resistant intracytoplasmic granules | IHC |
---|---|---|---|---|---|---|
Noussios et al (2010)11 | 3 | M | Tongue | Painful mass | Positive | — |
Eley et al (2010)9 | 24 | M | Tongue | Soft fluctuant swelling; asymptomatic | Positive | MyoD1 (+) |
Wakely et al (2009)17 | 8 | F | Oral cavity | NR | NR | NR |
Tapisiz et al (2008)12 | 18 | F | Tongue | Swelling, pain | NR | NR |
Correia-Silva et al (2006)13 | 17 | F | Tongue | Nodule at the dorsum surface of the tongue; asymptomatic | MSA(+) Myo D1 (+) Myogenin (+) Desmin (+) NSE (+) S100 (−) CK-AE1-AE3 (−) Vimentin (−) |
|
Souza et al (2005)5 | 13 | F | Tongue | Painless, erythematous nontender nodule | Positive | NSE (+) Vimentin (+) Desmin (+) S100 (+) CK–AE1–AE3 (+) EMA (+) Neurofilament (+) MSA(+) |
Kanhere et al (2005)14 | Mean 27, | 1 F | Tongue | Slow-growing mass; firm in consistency | Positive | NSE (−) CK (−) Vimentin (−) |
range 6–43 | 3 M | |||||
Kim et al (2005)15 | 16 4 22 |
M F M |
Tongue Tongue Cheek |
Painless swelling | Positive | Cytokeratin (−) |
Fanburg-Smith et al (2004)16 | Mean 8, range 3–21 |
5 F 7 M |
Tongue | Erythematous mass, pain, dysphagia, and dysphasia | Positive | MSA(+) Desmin (+) S100 (−) CK (−) Vimentin (−) Myo D1 (−) Myogenin (−) Myoglobin (−) |
Aiken and Stone (2003)7 | 34 | F | Tongue | Oral bleeding, tongue swelling, dysphonia, progressive dysphagia | Positive | S 100 (−) |
Richards et al (2003)4 | 16 | M | Mandible | Painless and progressive enlargement of the right mandibular angle | Positive | Vimentin (+) NSE (+) |
Charrier et al (2001)10 | 54 | F | Cheek | Large swelling, severe pain, trismus | Negative | Desmin (+) Vimentin (+) S100 (−) CK (–) |
Yoshida et al (2000)6 | 2 | F | Tongue | Painless mass | Positive | MyoD1 (+) Myoglobin (+) NSE (+) |
Kimi et al (2000)2 | 25 | F | Cheek | Painless | Positive | Anti–myoglobin (+) NSE (+) Sarcomeric actin (+) |
CK = cytokeratin; EMA = human epithelial membrane antigen; F = female; IHC = immunohistochemistry; M = male; MSA = muscle-specific-actin; NR = not reported; NSE = neuron-specific enolase; PAS = periodic acid-Schiff.