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. 2019 Feb 14;11:1517–1524. doi: 10.2147/CMAR.S176762

Table 1.

Prognostic value of Plk3 expression for the disease-free survival by Cox proportional hazards model

Variables Disease-free survival
HR (95% CI) P-value

Univariate analysis
Age (≥60 vs <60 years) 1.488 (0.968–2.287) 0.070
Gleason score (>7 vs =7 vs < 7) 9.464 (1.319–67.921) 0.025*
Tumor stage (T2–T4 vs T1) 2.972 (1.732–5.102) <0.001***
Lymph node stage (N1 vs N 0) 1.801 (1.111–2.920) 0.017
Distant metastasis (M1 vs M0) 0.049 (0–2488134.592) 0.740
PSA (≥4 vs <4) 3.410 (1.644–7.075) 0.001**
Plk3 expression (high vs low) 1.855 (1.048–3.285) 0.034*
Multivariate analysis
Gleason score (>7 vs = 7 vs < 7) 5.709 (0.789–41.328) 0.085
Tumor stage (T2–T4 vs T1) 2.763 (1.1607–4.751) <0.00024***
Plk3 expression (high vs low) 1.933 (1.091–3.639) 0.025*

Note:

*

P<0.05,

**

P<0.01, and

***

P<0.001. Statically significant P-values are shown in bold.

Abbreviations: Plk3, polo-like kinase 3; PSA, prostate-specific antigen.