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. 2019 Feb 18;12:1309–1318. doi: 10.2147/OTT.S184560

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© 2019 Zhao et al. This work is published and licensed by Dove Medical Press Limited

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Downregulated expression of NUCB2 inhibited the migration and invasion of thyroid cancer cells by regulating MMP2 and MMP9.

Notes: (A) Transwell assay demonstrated that the ability of invasion in shRNA group was significantly decreased comparing to control group (n=3, P<0.05, respectively). (B and C). Western blot of MMP2 and MMP9 and its quantification showed that the expression of MMP2 and MMP9 were reduced in shRNA group when compared to control group (n=3, P<0.05, respectively). *P<0.05.