Figure 5.
The influence of NUCB2 on tumor growth of thyroid cancer in mice.
Notes: (A) Representative images of tumors from both groups are shown. Tumor volumes of shRNA group were smaller than those of the control group (n=6, P<0.05). (B and C) Both immunohistochemistry and Western blot demonstrated that the expression of NUCB2 was dramatically decreased in mice tumors (n=6, P<0.05, respectively), which suggested a successful construction of NUCB2 knocked down model in mice. *P<0.05.