Table S1.
Multivariate analysis of overall survival in 371 HCC specimens
| Variables | Multivariate analysis
|
||
|---|---|---|---|
| HR | 95% CI | P-value | |
|
| |||
| Gender | 2.087 | 0.929–4.688 | 0.075 |
| Age (years) | 1.039 | 1.011–1.068 | 0.006* |
| Weight (kg) | |||
| Adjacent tissue inflammation | |||
| Albumin (g/L) | |||
| Child-Pugh stage | |||
| Creatinine | |||
| AFP (ng/mL) | 1.000 | 1.000–1.000 | 0.232 |
| PLT (10e9/L) | |||
| Prothrombin time (seconds) | |||
| Total bilirubin (μmol/L) | 0.076 | 0.006–0.989 | 0.049* |
| Cirrhosis | |||
| Histologic grade | 1.823 | 1.118–2.974 | 0.016* |
| Pathologic stage | 2.215 | 1.477–3.322 | 0.000* |
| E2F5 (scores) | 1.374 | 1.045–1.807 | 0.023* |
| E2F6 (scores) | 2.074 | 1.128–3.815 | 0.019* |
Notes: Statistical analysis was performed by Cox test analysis.
*
P-values with significant difference.
Abbreviations: AFP, alpha fetoprotein; HCC, hepatocellular carcinoma; PLT, platelet.