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. 2019 Feb 13;11:1443–1451. doi: 10.2147/CMAR.S188020

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© 2019 Li et al. This work is published and licensed by Dove Medical Press Limited

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Increased cell proliferation and migration and decreased cell apoptosis in claudin-7 KD cells.

Notes: (A) The detection of cell viability of CRC cell line HCT116CON and stable transfected cell lines HCT116NC and HCT116KD. Cell viability in group HCT116KD was significantly higher than that in group HCT116NC. *P<0.05. (B) The detection of apoptosis ability of CRC cell line HCT116CON and stable transfected cell lines HCT116NC and HCT116KD. The apoptosis ability in group HCT116KD was significantly lower than that in group HCT116NC. *P<0.05. (C, D) The detection of migration ability of CRC cell line HCT116CON and stable transfected cell lines HCT116NC and HCT116KD. Compared with group HCT116NC, the migration ability of cells in HCT116KD group was enhanced. *P<0.05 (magnification: 40×).

Abbreviations: CON, control; NC, negative control; KD, knockdown; CRC, colorectal cancer.