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. 2018 Feb 27;18:230. doi: 10.1186/s12885-018-4151-x

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Patients contributing the histologically normal breast tissue samples analyzed in the present study. Patient groups considered for inclusion in the investigation were selected based on four different breast surgery indications: cancer but no BRCA1/2 mutation; cancer and BRCA1/2 mutation; BRCA1/2 carrier status but no cancer; mammoplasty. The same set of patients was evaluated in previous studies [14, 19, 20]