Table 1.
Baseline clinical and biochemical data of cases and controls
| Index | Controls, n = 170 | Cases, n = 127 | p |
|---|---|---|---|
| Age, years | 52.0 ± 9.0 | 53.2 ± 7.1 | NS |
| Sex (male), n (%) | 61 (36%) | 46 (36%) | NS |
| Weight, kg | 64.7 ± 9.8 | 83.5 ± 14.1 | 0.00001 |
| Essential hypertension, n (%) | 0 | 69 (54.3%) | – |
| SBP, mm Hg | 122.0 ± 10.6 | 148.6 ± 27.0 | 0.00001 |
| DBP, mm Hg | 79.3 ± 9.3 | 91.7 ± 14.5 | 0.00001 |
| Type 2 diabetes, n (%) | 0 | 69 (54%) | – |
| Blood glucose, mmol/l | 5.20 [5.01;5.48] | 7.33 [5.49;8.48] | 0.001 |
| MS, n (%) | 0 | 114 (90%) | – |
| Obesity, n (%) | 0 | 95 (75%) | – |
| BMI, kg/m2 | 24.1 ± 2.7 | 31.5 ± 4.1 | 0.00001 |
| WC (cm) | 83.2 ± 8.6 | 104.1 ± 9.2 | 0.00001 |
| HC (cm) | 95.6 ± 7.8 | 109.5 ± 8.6 | 0.00001 |
| TC, mmol/l | 5.0 ± 0.9 | 5.1 ± 1.0 | NS |
| HDLC, mmol/l | 3.2 ± 0.8 | 1.0 ± 0.3 | 0.00001 |
| LDLC, mmol/l | 1.3 ± 0.4 | 3.2 ± 0.9 | 0.00001 |
| TG, mmol/l | 1.2 ± 0.7 | 2.1 ± 1.5 | 0.00001 |
| НОМА-IR | 0 | 46 (36%) | – |
| Insulin, μIU/ml | 5.08 [3.35;6.65] | 12.7 [7.52;15.90] | 0.001 |
MS metabolic syndrome, WC waist circumference, HC hip circumference, SBP systolic blood pressure, DBP diastolic blood pressure, BMI body mass index, TC total cholesterol, HDLC high-density lipoprotein cholesterol, LDLC low-density lipoprotein cholesterol, TG triglycerides, NS non-significant, р probability value