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. 2018 Feb 27;18:27. doi: 10.1186/s12871-018-0489-5

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Serum levels of NAEs and endocannabinoids in patients receiving intrathecal morphine or placebo. The levels of PEA, OEA, AEA, and 2-AG were quantified in serum obtained preoperatively and 4 h after TKA surgery. *, p < 0.05; **, p < 0.01; ***, p < 0.001