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. 2018 Feb 27;18:3. doi: 10.1186/s12899-018-0037-z

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Comparable BA-induced inflammation in Alk3^fl/fl; Alb-Cre mice and Alk3^fl/fl mice. a Granulocytes from Alk3^fl/fl and Alk3^fl/fl; Alb-Cre mice 14 days after heat-killed Brucella abortus (BA) or saline injection (*P = 0.01: Alk3^fl/fl injected with saline [n = 4] vs Alk3^fl/fl injected with BA [n = 4]; *P = 0.01: Alk3^fl/fl; Alb-Cre injected with saline [n = 4] vs Alk3^fl/fl; Alb-Cre injected with BA [n = 6]), and (b) Relative hepatic IL-6 mRNA levels from Alk3^fl/fl and Alk3^fl/fl; Alb-Cre mice 14 days after BA administration (*P = 0.03: Alk3^fl/fl injected with saline [n = 3] vs Alk3^fl/fl injected with BA [n = 5]; **P = 0.01: Alk3^fl/fl; Alb-Cre injected with saline [n = 4] vs Alk3^fl/fl; Alb-Cre injected with BA [n = 6]). c Relative hepatic TNF-α mRNA levels (*P = 0.04: Alk3^fl/fl injected with saline [n = 3] vs Alk3^fl/fl injected with BA [n = 4]; *P = 0.01: Alk3^fl/fl; Alb-Cre injected with saline [n = 5] vs Alk3^fl/fl; Alb-Cre injected with BA [n = 6]). d Relative hepatic HO-1 mRNA levels (*P = 0.01: Alk3^fl/fl injected with saline [n = 4] vs Alk3^fl/fl injected with BA [n = 6]; *P = 0.01: Alk3^fl/fl; Alb-Cre injected with saline [n = 4] vs Alk3^fl/fl; Alb-Cre injected with BA [n = 6])