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. 2018 Mar 14;19:197. doi: 10.1186/s12864-018-4556-6

Table 2.

Number of deregulated miRNAs and mRNAs in aneuploid cell lines

HCT116 RPE1
5/4 18/3 c2 *3/3 c11 *8/3 c7 5/3 12/3 *7/3 *21/3
miRNAs with a mean count ≥ 10 249 280 279 293 237 247 231
Significantly deregulated miRNAs log2 Fold Change 0.6–0.6 (padj. < 0.05) 74 57 27 44 74 33 23
Percentage of significantly deregulated miRNAs 29.7 20.4 9.7 15.0 31.2 13.4 10.0
mRNAs with a mean count ≥ 10 13,887 n.a. n.a. 13,873 13,278 13,101 13,101
Significantly deregulated mRNAs log2 Fold Change 0.6–0.6 (padj. < 0.05) 2885 n.a. n.a. 410 2210 434 434
Percentage of significantly deregulated mRNAs 20.8 n.a. n.a. 3.0 16.6 n.a. 3.3

Cell lines with * contain H2B-GFP