Table 1.
Baseline characteristics
| Entire cohort | Class 1 | Class 2 | Class 3 | |
|---|---|---|---|---|
| Number of participants | 1160 | 119 | 888 | 153 |
| Duration of follow-up (months) | 12.8 ± 5.9 | 13.6 ± 4.2 | 13.3 ± 5.7 | 9.1 ± 6.7 |
| Age | 75.6 ± 8.1 | 73.1 ± 8.9 | 76.1 ± 7.8 | 74.7 ± 8.6 |
| Gender | ||||
| Female | 590 (50.9) | 58 (48.7) | 443 (49.9) | 89 (58.2) |
| Male | 472 (40.7) | 50 (42.0) | 367 (41.3) | 55 (35.9) |
| Missing | 98 (8.4) | 11 (9.2) | 78 (8.8) | 9 (5.9) |
| Education | 14.0 ± 3.2 | 14.8 ± 3.2 | 13.9 ± 3.3 | 14.0 ± 2.9 |
| Race | ||||
| Asian | 8 (0.7) | 1 (0.8) | 6 (0.7) | 1 (0.7) |
| African American | 59 (5.1) | 6 (5) | 45 (5.1) | 8 (5.2) |
| White | 1007 (86.8) | 103 (86.8) | 771 (86.8) | 133 (86.9) |
| Other | 28 (2.4) | 0 (0) | 22 (2.5) | 6 (3.9) |
| Missing | 58 (5) | 9 (7.6) | 44 (5) | 5 (3.3) |
| Marital status | ||||
| Divorced | 70 (6.0) | 8 (6.7) | 55 (6.2) | 7 (4.6) |
| Married | 800 (69.0) | 90 (75.6) | 603 (67.9) | 107 (69.9) |
| Never married | 26 (2.2) | 3 (2.5) | 22 (2.5) | 1 (0.7) |
| Widowed | 243 (20.9) | 16 (13.4) | 195 (22.0) | 32 (20.9) |
| Missing | 21 (1.8) | 2 (1.7) | 13 (1.5) | 6 (3.9) |
| ApoE4 carriers (%)a | 63.5 | 65.7 | 63.6 | 62.6 |
| Statin users | 311 (26.8) | 23 (19.3) | 254 (28.4) | 34 (22.2) |
| Baseline ADAS-cog | 23.6 ± 9.6 | 26.5 ± 6.9 | 20.4 ± 6.7 | 40.9 ± 6.3 |
Baseline characteristics of participants in the entire cohort and in each of the resulting latent classes (in the three-class model). Data presented as mean ± standard deviation or n (%) unless stated otherwise
ADAS-cog Alzheimer’s Disease Assessment Scale—cognitive subscale, ApoE4 Apolipoprotein E, allele 4
aPercent of those participants with relevant information available