Fig. 2.

Concordance between DNA methylation variation and genetic variation depends on genomic context. (A) Correlation between pairwise genetic covariance between species and pairwise covariance in DNA methylation levels, for CpG sites stratified by genomic context and mean DNA methylation level. Each point represents n = 2,658–604,775 CpG sites. (B) Estimated mean rate of change in DNA methylation levels per million years, stratified by genomic context. Error bars represent the standard error for each estimate.