Table 2.
SLC4A11 and mutants current densities (a-e are indicated in (Fig. 2).
| Current Densities (pA/pF) | P (vs WT) | P (vs EV) | ||
|---|---|---|---|---|
| WT (n=17) | a | −6.42 ± 1.67 | N.C. | P<0.05 |
| b | 1.04 ± 0.36 | N.C. | N.S. | |
| c | −22.09 ± 2.24 | N.C. | P<0.001 | |
| d | −1.92 ± 0.61 | N.C. | N.S | |
| e | −4.60 ± 0.50 | N.C. | P<0.05 | |
| C386R (n=8) | a | −0.97 ± 0.51 | P<0.05 | P<0.05 |
| b | −0.38 ± 0.30 | P<0.05 | N.S. | |
| c | −3.00 ± 0.63 | P<0.001 | P<0.05 | |
| d | −3.93 ± 0.97 | P<0.05 | P<0.05 | |
| e | −4.05 ± 0.99 | N.S | P<0.05 | |
| W240S (n=8) | a | −0.56 ± 0.28 | P<0.05 | N.S. |
| b | −0.30 ± 0.19 | P<0.05 | N.S. | |
| c | −1.64 ± 0.24 | P<0.001 | P<0.05 | |
| d | −1.28 ± 0.29 | N.S. | N.S. | |
| e | −1.23 ± 0.32 | P<0.05 | P<0.05 | |
| R125H (n=6) | a | 0.12 ± 0.19 | P<0.05 | N.S. |
| b | −0.62 ± 0.45 | N.S. | N.S. | |
| c | −0.66 ± 0.11 | P<0.001 | N.S. | |
| V507I (n=6) | c | −0.74 ± 0.24 | P<0.001 | N.S. |
| N693A (n=5) | a | 0.91 ± 0.26 | P<0.05 | N.S. |
| b | −0.29 ± 0.09 | N.S. | N.S. | |
| c | −0.60 ± 0.19 | P<0.001 | N.S. | |
| EV (n=6) | a | −0.19 ± 0.10 | P<0.05 | N.C. |
| b | −0.11 ± 0.05 | N.S. | N.C. | |
| c | −0.58 ± 0.06 | P<0.001 | N.C. | |
| d | −1.14 ± 0.28 | N.S | N.C. | |
| e | −1.34 ± 0.36 | P<0.05 | N.C. | |
N.C. stands for not compared; N.S. stands for no significant difference. Each individual measurement was taken from one individual cell per coverslip. “n” represents the number of tested individual cells.