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. Author manuscript; available in PMC: 2020 Mar 1.
Published in final edited form as: Exp Eye Res. 2018 Dec 10;180:63–74. doi: 10.1016/j.exer.2018.11.020

Figure 2. Diabetic RPEIRKO mice exhibit reduced plasma insulin and elevated blood and retinal glucose concentrations.

Figure 2.

(A) Systemic non-fasting blood glucose concentration. (B) Body weight of each cohort of mice measured at the time of each electroretinogram session (2 weeks and 4 weeks). (C) Plasma insulin levels measured by ELISA after 4 weeks of diabetes. (D) Retinal glucose levels measured by hexokinase assay at 4 weeks of diabetes. (E) Retinal insulin levels relative to protein concentration at 2 weeks of diabetes. Data points indicate the mean ± SEM. At each time point, n≥3 for each group. *p≤0.05, **p≤0.001, ***p≤0.0001 by one-way ANOVA with Tukey’s post hoc analysis.