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. Author manuscript; available in PMC: 2020 Mar 1.
Published in final edited form as: Exp Eye Res. 2018 Dec 10;180:63–74. doi: 10.1016/j.exer.2018.11.020

Figure 4. Diabetes does not affect diameter or area of RPE cells in IR flox and RPEIRKO mice.

Figure 4.

(A) Representative flat mount images from IR flox and RPEIRKO mice at 2 weeks of diabetes stained with phalloidin. At least 20 cells per flatmount were analyzed by Image J software for RPE cell area (B) and diameter (C). (D) High magnification images from semi-thin sections of each mouse genotype/treatment at 4weeks following onset of diabetes. Scale bar = 10μm. Images were analyzed for RPE thickness with Image J software (E). Statistical significance was determined by one-way ANOVA with Tukey post hoc test. n≥3 for each group.