Figure 8. Diabetes induces reductions in the RPE-dependent c-wave regardless of IR-mediated signaling in the RPE.
(A) Representative c-wave recordings at 2 and 4 weeks of diabetes for each group. Control (CNTL) mice are represented by black traces and STZ-injected diabetic mice by gray traces. (B) Amplitude of the c-wave at each time point. (C) The relative amplitude of the c-wave plotted as a function of the relative a-wave amplitude. n≥5 for each group at each time point.