Table 3.
Metabolically Healthy Overweight/Obese (MHO) phenotype | Metabolically Unhealthy Overweight/Obese (MUO) phenotype | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
DII tertile 1 | DII tertile 2 |
DII tertile 3 |
P trend | HR for a 1 SD increase in DII |
DII tertile 1 |
DII tertile 2 |
DII tertile 3 |
P trend | HR for a 1 SD increase in DII |
|
No. of participants | 570 | 611 | 634 | 674 | 634 | 610 | ||||
No. of person years | 10398 | 11086 | 11478 | 11407 | 10315 | 9732 | ||||
Deaths from all causes, n | 73 | 80 | 93 | 188 | 213 | 221 | ||||
1.00 (ref.) | 0.78 (0.56–1.11) | 0.77 (0.50–1.20) | 0.27 | 0.93 (0.76–1.13) | 1.00 (ref.) | 1.41 (1.15–1.73) | 1.44 (1.11–1.86) | 0.008 | 1.08 (0.99–1.18) | |
CVD Deaths, n | 18 | 20 | 29 | 55 | 61 | 69 | ||||
1.00 (ref.) | 0.84 (0.32–2.18) | 1.05 (0.56–1.98) | 0.75 | 1.11 (0.79–1.55) | 1.00 (ref.) | 2.48 (1.79–3.44) | 3.29 (2.01–5.37) | <0.001 | 1.40 (1.18–1.66) | |
* Cancer Deaths, n | 21 | 20 | 14 | 46 | 53 | 55 | ||||
1.00 (ref.) | 0.86 (0.43–1.70) | 0.42 (0.13–1.34) | 0.12 | 0.75 (0.50–1.13) | 1.00 (ref.) | 1.20 (0.80–1.78) | 1.26 (0.76–2.08) | 0.35 | 1.05 (0.85–1.30) |
Data are presented as hazard ratio (95% confidence interval).
Abbreviations: DII, dietary inflammatory index; CVD, cardiovascular disease.
Multivariable adjusted hazard ratio is adjusted for age, sex, race/ethnicity(non-Hispanic white, non-Hispanic black, or others), educational attainment(<12 years, 12 years, or >12 years of education), income[low (poverty income ratio (PIR) ≤ 1.3), middle (1.3<PIR ≤ 3.5), and high (PIR>3.5)], smoking status(never, former, and current), level of physical activity(inactive, insufficient activity, recommended activity), and body mass index.
Those who had a history of skin cancer were additionally excluded.