Figure 9.

Correlation between HLA-G levels and composition of immune cell population in ascitic clusters.

A positive correlation coefficient of HLA-G1 + G5 was detected only with CD45⁺RO (r_s = 0.44), CD4⁺CD25⁺CD127⁻ (r_s = 0.36), and CD4⁺ (r_s = 0.26) subpopulations, whereas a negative coefficient of correlation of HLA-G1 + G5 was detected for CD3⁻CD56+ (r_s = −0.63) subpopulation. We used another antibody (5A6G7) to detect sHLA-G5 in ascites. A strong negative correlation was found for sHLA-G5 with CD8⁺ (r_s = −0.63), CD3⁻CD56⁺ (r_s = −0.58), and CD4⁺CD45RO (r_s = −0.37), whereas a positive correlation was found with CD4⁺ (r_s = 0.35) and CD4⁺CD25⁺CD127⁻ (r_s = 0.93).