Table 2.
Time to detection (TTD) in pediatric blood culture (BC) bottles from the VIRTUO, BTA3D, and BACTEC BC systems.
| Species isolates (n) | TTD (median, h) by | ||||
|---|---|---|---|---|---|
| VIRTUO | BTA3D | BACTEC | |||
| VIRTUO vs. BTA3D (p)a | VIRTUO vs. BACTEC (p)a | ||||
| Gram-negative species (130) | 10.1 | 12.0 | 10.8 | < 0.001 | < 0.001 |
| Acinetobacter baumannii (10) | 10.0 | 11.2 | 11.1 | 0.005 | 0.005 |
| Citrobacter freundii (10) | 11.1 | 12.4 | 11.5 | 0.005 | 0.005 |
| Enterobacter cloacae (10) | 9.5 | 11.3 | 10.4 | 0.005 | 0.02 |
| Escherichia coli (10) | 9.1 | 11.1 | 10.7 | 0.005 | 0.005 |
| Klebsiella aerogenes (10) | 9.5 | 11.4 | 10.5 | 0.005 | 0.04 |
| Klebsiella oxytoca (10) | 9.8 | 12.1 | 11.2 | 0.005 | 0.005 |
| Klebsiella pneumoniae (10) | 9.8 | 12.1 | 11.1 | 0.005 | 0.009 |
| Morganella morganii (10) | 10.1 | 11.3 | 9.8 | 0.005 | NS |
| Proteus mirabilis (10) | 11.1 | 13.0 | 12.4 | 0.005 | 0.005 |
| Pseudomonas aeruginosa (10) | 13.5 | 15.3 | 15.3 | 0.005 | 0.005 |
| Salmonella spp. (10) | 7.9 | 10.2 | 9.1 | 0.005 | 0.005 |
| Serratia marcescens (10) | 9.4 | 11.3 | 10.1 | 0.005 | 0.02 |
| Stenotrophomonas maltophilia (10) | 17.2 | 17.3 | 15.4 | NS | 0.005 |
| Gram-positive species (130) | 13.5 | 15.2 | 16.1 | < 0.001 | < 0.001 |
| Enterococcus faecalis (10) | 8.4 | 10.3 | 9.5 | 0.005 | 0.005 |
| Enterococcus faecium (10) | 9.6 | 12.2 | 12.0 | 0.005 | 0.005 |
| Listeria monocytogenes (10) | 15.3 | 17.1 | 16.4 | 0.005 | 0.005 |
| Staphylococcus aureus (10) | 13.3 | 15.2 | 16.1 | 0.005 | 0.005 |
| Staphylococcus capitis (10) | 14.4 | 17.5 | 17.5 | 0.005 | 0.005 |
| Staphylococcus epidermidis (10) | 14.2 | 16.2 | 17.2 | 0.005 | 0.005 |
| Staphylococcus haemolyticus (10) | 14.2 | 17.2 | 18.1 | 0.005 | 0.005 |
| Staphylococcus hominis (10) | 17.2 | 18.4 | 19.0 | 0.005 | 0.005 |
| Staphylococcus lugdunensis (10) | 13.6 | 16.3 | 16.3 | 0.005 | 0.005 |
| Streptococcus agalactiae (10) | 8.1 | 10.3 | 9.4 | 0.005 | 0.005 |
| Streptococcus mitis (10) | 9.4 | 12.4 | 12.2 | 0.005 | 0.005 |
| Streptococcus pneumoniae (10) | 13.5 | 14.5 | 14.4 | 0.005 | 0.005 |
| Streptococcus pyogenes (10) | 10.1 | 12.3 | 11.3 | 0.005 | 0.005 |
| Yeast species (50) | 25.2 | 28.8 | 24.8 | < 0.001 | NS |
| Candida albicans (10) | 25.2 | 25.8 | 24.8 | 0.005 | NS |
| Candida glabrata (10) | 31.1 | 32.6 | 31.3 | 0.009 | NS |
| Candida krusei (10) | 18.3 | 19.5 | 18.5 | 0.005 | NS |
| Candida parapsilosis (10) | 32.4 | 33.5 | 31.5 | 0.005 | 0.01 |
| Candida tropicalis (10) | 17.4 | 18.2 | 18.4 | 0.005 | 0.005 |
| Total (310) | 11.2 | 13.0 | 12.5 | < 0.001 | < 0.001 |
a
Statistically not significant (NS) p > 0.05.