Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Feb 19;9:28. doi: 10.3389/fcimb.2019.00028

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2019 Nearing, Connors, Whitehouse, Van Limbergen, Macdonald, Kulkarni and Langille.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Taxonomic contributions to pathways that were significantly different between samples from NIC patients and IC patients from metagenomic shotgun sequencing. All 42 Metacyc pathways represented in the figure were determined to be significantly different in relative abundance between NIC and IC patients (Wilcoxon rank sum test with correction for false discovery at an alpha value of 0.05). Significantly different pathways were then divided into either being biosynthetic, degradation or other pathway types. Contributions to the relative abundance of these pathways' are colored by genus of the contributing bacteria. Genera that contributed less than a total of 0.01% relative abundance to overall pathways were collapsed into “Other.” Note some pathways have total relative abundances of 0 due to no single species contain all genes required to contribute to the pathway.