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. 2019 Feb 22;11:180–190. doi: 10.1016/j.dadm.2018.12.008

Table 4.

Sample size for a 2-year trial by tracers (using RSF-PVC-based amyloid burden measurements)

Tracer Reduction in the annual rate of change
20% less 40% less 60% less 80% less
AV45 2156 539 240 135
PiB 305 77 34 20

Abbreviations: AV45, florbetapir; PiB, Pittsburgh compound B; PVC, partial volume correction; RSF, regional spread function.