Table 1.
Baseline demographics and clinical characteristics
| RRMS | SPMS | PPMS | P‐value | |
|---|---|---|---|---|
| Number of patients (%) | 151 (87.8) | 14 (8.1) | 7 (4.1) | <0.0001 |
| Age at first OCT; mean, years (SD) | 39.4 (9.9) | 51.7 (5.8) | 49.9 (8.3) | <0.0001 a |
| Females; n (%) | 120 (79.5) | 10 (71.4) | 4 (57.1) | 0.22b |
| Race; n (%) | ||||
| Caucasian | 122 (80.8) | 14 (100.0) | 6 (85.7) | 0.74b |
| African American | 21 (13.9) | 0 (0.0) | 1 (14.3) | |
| Hispanic | 3 (2.0) | 0 (0.0) | 0 (0.0) | |
| Asian‐Pacific Islander | 1 (0.7) | 0 (0.0) | 0 (0.0) | |
| Other | 4 (2.7) | 0 (0.0) | 0 (0.0) | |
| Disease Duration; mean, years (SD) | 15.9 (6.7) | 30.4 (9.0) | 16.1 (3.9) | <0.0001 a |
| Optic neuritis history; n (%) | 70 (46.4) | 6 (42.9) | 0 (0.0) | 0.11b |
| Follow‐up duration; mean, years (SD) | 9.4 (0.7) | 9.5 (0.7) | 9.5 (0.5) | 0.90a |
| Baseline EDSS; mean (SD) | 2.0 (1.4) | 5.5 (1.9) | 4.8 (1.5) | <0.0001 b |
RRMS, relapsing remitting multiple sclerosis; SPMS, secondary progressive multiple sclerosis; PPMS, primary progressive multiple sclerosis; OCT, Optical coherence tomography; EDSS, Expanded Disability Status Scale.
a
Determined by Kruskal–wallis equality‐of‐population rank test.
b
Determined by Fisher'sexact test.