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. 2019 Feb 25;7(4):e14009. doi: 10.14814/phy2.14009

Table 2.

Adenosine: rest and exercise vascular hemodynamics

Variable Saline (control) Bout 1 Bout 2 Bout 3 Bout 4 Bout 5
Time (minutes) 5 30 60 120 150
HR
Rest 59 ± 2 60 ± 2 58 ± 2 61 ± 2 59 ± 2 59 ± 2
Exercise 63 ± 2 62 ± 2 63 ± 2 62 ± 2 64 ± 2 65 ± 2
MAP
Rest 93 ± 3 92 ± 3 95 ± 3 97 ± 3 96 ± 3 96 ± 3
Exercise 98 ± 4 95 ± 3 96 ± 3 97 ± 4 102 ± 4 101 ± 4
FBF (mL/min/100 mL FAV)
Rest 4.3 ± 0.6 20.9 ± 2.5* 24.8 ± 2.5* 22.4 ± 2.2* 25.8 ± 5.1* 20.4 ± 1.4*
Exercise 28.6 ± 4.3 52.0 ± 4.9* 54.2 ± 5.4* 55.5 ± 6.9* 55.7 ± 6.3* 56.3 ± 5.3*
(Δ) FBF from rest (mL/min/100 mL FAV)
Exercise 24.3 ± 3.8 31.1 ± 5.7 29.4 ± 4.9 33.2 ± 6.3 29.9 ± 4.5 35.9 ± 5.0
Δ FVC from rest (mL/min/100 mmHg/100 mL FAV)
Exercise 26.4 ± 3.7 32.1 ± 5.5 30.3 ± 4.7 34.5 ± 6.2 32.5 ± 4.3 37.2 ± 5.1

Values are means ± SE for all nine subjects. MAP, mean arterial pressure.

*

< 0.05 from control. FBF, forearm blood flow; Delta FBF was calculated as bout exercise FBF – bout baseline FBF; FVC, forearm vascular conductance; Delta FVC was calculated as bout exercise FVC‐bout baseline FVC. 100.