Table 1.
The Relationship between ZNF280A IHC Expression Level and Clinical Pathological Characteristics in 378 Patients with Colorectal Cancer
| Parameter | Number of Cases | ZNF280A IHC Expression |
p Value |
|
|---|---|---|---|---|
| Low | High | |||
| Location | 198 | 180 | ||
| Rectum | 118 | 59 | 59 | 0.532 |
| Colon | 260 | 139 | 121 | |
| Gender | ||||
| Female | 169 | 84 | 85 | 0.349 |
| Male | 209 | 114 | 95 | |
| Age (years) | ||||
| ≤60 | 133 | 65 | 68 | 0.314 |
| >60 | 245 | 133 | 112 | |
| Grade | ||||
| G1–G2 | 341 | 184 | 157 | 0.062 |
| G3 | 37 | 14 | 23 | |
| T classification | ||||
| T1–2 | 79 | 56 | 23 | <0.001 |
| T3–4 | 299 | 142 | 157 | |
| N classification | ||||
| N0 | 218 | 148 | 70 | <0.001 |
| N1–2 | 160 | 50 | 110 | |
| M classification | ||||
| M0 | 331 | 185 | 146 | <0.001 |
| M1 | 47 | 13 | 34 | |
| Stage | ||||
| I–II | 213 | 145 | 68 | <0.001 |
| III–IV | 165 | 53 | 112 | |
| Chemotherapeutic response | ||||
| Sensitivity | 39 | 22 | 17 | 0.001 |
| Resistance | 36 | 7 | 29 | |