Table 1. Patient Characteristic of Nodular IMA and Invasive Non-Mucinous ADC.
| Characteristics | IMA (n = 35) | Invasive Non-Mucinous ADC (n = 329) | P |
|---|---|---|---|
| Age (years), mean ± SD | 57.7 ± 9.4 | 60.5 ± 9.5 | 0.100 |
| Smoking | 0.239 | ||
| Never | 25 (71) | 201 (61) | |
| Ever | 10 (29) | 128 (39) | |
| Gender | 0.261 | ||
| Male | 13 (37) | 155 (47) | |
| Female | 22 (63) | 174 (53) | |
| Types of surgery | 0.855 | ||
| Wedge resection | 5 (14) | 46 (14) | |
| Lobectomy | 30 (86) | 280 (85) | |
| Pneumonectomy | 0 (0) | 3 (1) | |
| T classification* | 0.984 | ||
| T1a | 21 (60) | 191 (58) | |
| T1b | 13 (37) | 126 (38) | |
| T2a | 1 (3) | 11 (3) | |
| T3 | 0 (0) | 1 (0) | |
| N classification | 0.025† | ||
| N0 | 35 (100) | 274 (83) | |
| N1 | 0 (0) | 40 (12) | |
| N2 | 0 (0) | 15 (5) | |
| Morphologic evaluation | |||
| Size (mm) | 21 ± 7 | 21 ± 6 | 0.757 |
| TDR | 39.9 ± 26.3 | 50.9 ± 33.1 | 0.069 |
| Margin | 0.101 | ||
| Smooth | 6 (17) | 100 (30) | |
| Lobulated or spiculated | 29 (83) | 229 (70) | |
| Metabolic evaluation | < 0.001† | ||
| SUVmax, mean ± SD | 1.8 ± 2.0 | 4.6 ± 4.2 | |
| Morphologic malignancy | 24 (68) | 152 (46) | 0.012† |
| Metabolic malignancy | 5 (14) | 170 (52) | < 0.001† |
| M-M dissociation | < 0.001† | ||
| Positive | 19 (54) | 34 (10) | |
| Negative | 16 (46) | 295 (90) |
*All tumors were less than 3 cm in diameter. Thirteen tumors of T2a and T3 were staged due to visceral pleural or chest wall invasion, †p value < 0.05. ADC = adenocarcinoma, IMA = invasive mucinous adenocarcinoma, M-M = morphologic-metabolic, SD = standard deviation, SUVmax = maximum standardized uptake value, TDR = tumor shadow disappearance rate