Table 1.
Addition of B. bifidum to faecal suspensions incubated in the presence of HMOs enriches the Bifidobacterium population (species other than B. bifidum) in the culture. Prevalence was calculated by dividing total bifidobacterial 16S rRNA gene counts (except for B. bifidum) by total bacterial 16S rRNA gene counts. The data were adapted from the paper by Gotoh et al., 2018
| Bifidobacterium bifidum strain added to faecal suspension | Faecal suspension (Age/Delivery mode) | Child A (4 years/vaginal) | Child B (5 years/vaginal) | Infant C (4 months/caesarean) | Adult D (30 years/no data) | Adult E (39 years/no data) |
|---|---|---|---|---|---|---|
| None added | Total bacteria (copies/ml; ×1013) | 1.4 ± 0.5 | 1.7 ± 0.1 | 0.78 ± 0.01 | 1.7 ± 0.1 | 2.5 ± 0.0 |
| Prevalence of other bifidobacterial species in total bacteria (%) | 0.0050 | 2.6 | 0.00034 | 0.37 | 5.0 | |
| JCM1254 | Total bacteria (copies/ml×; ×013) | 2.0 ± 0.1 | 2.5 ± 0.4 | 1.7 ± 0.0 | 2.2 ± 0.1 | 2.4 ± 0.1 |
| Prevalence of other bifidobacterial species in total bacteria (%) | 0.21 | 4.3 | 0.27 | 2.4 | 3.6 | |
| JCM7004 | Total bacteria (copies/ml; × 1013) | 1.6 ± 0.1 | 2.0 ± 0.2 | 1.3 ± 0.0 | 2.2 ± 0.1 | 2.6 ± 0.1 |
| Prevalence of other bifidobacterial species in total bacteria (%) | 0.58 | 3.4 | 0.81 | 2.8 | 4.4 | |
| TMC3108 | Total bacteria (copies/ml; ×1013) | 2.2 ± 0.8 | 1.4 ± 0.1 | 1.1 ± 0.0 | 2.1 ± 0.1 | 2.7 ± 0.1 |
| Prevalence of other bifidobacterial species in total bacteria (%) | 1.0 | 4.9 | 1.6 | 0.48 | 4.4 | |
| TMC3115 | Total bacteria (copies/ml; ×1013) | 1.3 ± 0.0 | 1.6 ± 0.1 | 1.4 ± 0.0 | 2.0 ± 0.1 | 2.5 ± 0.1 |
| Prevalence of other bifidobacterial species in total bacteria (%) | 5.3 | 1.9 | 2.0 | 4.4 | 3.8 |