Fig. 5.
Time series analyses. a ROI activity at the end of the encoding phase (TR9) for the manipulation minus maintenance trials. There were no significant differences in activity for these conditions prior to the retro-cue. Error bars represent standard error of the mean. b ROI activity just prior to the probe (TR14). There were significant increases in activity for the manipulation vs. maintenance trials in all ROIs. c–e Plotting the entire BOLD time series averaged across all four ROIs showed that in addition to the effects of manipulation there were also effects of both domain and load. Therefore, the set of brain regions associated with manipulation demands is also sensitive to other aspects of WM