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. 2019 Feb 25;9:2655. doi: 10.1038/s41598-019-39658-5

Table 4.

Odds ratios and adjusted odds ratios of asthma, rhinoconjunctivitis and eczema symptoms for birthweight, gestational age, and light-for-dates of the participating children.

Characteristics N Cases % Asthma symptoms crude OR (95% CI) Asthma symptoms adjusted ORa (95% CI) Cases % Rhinoconjuncti-vitis symptoms crude OR (95% CI) Rhinoconjuncti-vitis symptoms adjusted ORa (95% CI) Cases % Eczema symptoms crude OR (95% CI) Eczema symptoms adjusted ORa (95% CI)
Birthweight
<2500 g 27 3 11.1 2.41 (0.70–8.23) 2.93 (0.83–10.40) 4 14.8 1.35 (0.46–3.97) 1.56 (0.52–4.69) 6 22.2 4.25 (1.67–10.85) 5.13 (1.93–13.62)
<= 2500 g 1175 58 4.9 1.00 1.00 134 11.4 1.00 1.00 74 6.3 1.00 1.00
Birthweight
<2500 g 27 3 11.1 2.42 (0.71–8.29) 2.95 (0.83–10.46) 4 14.8 1.33 (0.45–3.90) 1.55 (0.51–4.64) 6 22.2 4.44 (1.74–11.36) 5.31 (2.00–14.12)
2500–4000 g 1141 56 4.8 1.00 1.00 132 11.6 1.00 1.00 69 6.1 1.00 1.00
>4000 g 34 2 5.8 1.21 (0.28–5.18) 1.24 (0.28–5.38) 2 5.9 0.48 (0.11–2.02) 0.50 (0.11–2.15) 5 14.7 2.68 (1.01–7.14) 2.54 (0.92–6.98)
Gestational age
<37 weeks (preterm) 36 2 5.6 1.10 (0.26–4.70) 1.14 (0.26–4.97) 5 13.9 1.25 (0.48–3.28) 1.45 (0.54–3.90) 2 5.6 0.82 (0.19–3.48) 0.84 (0.20–3.63)
>= 37 weeks 1166 59 5.1 1.00 1.00 133 11.4 1.00 1.00 78 6.7 1.00 1.00
Light-for-dates
Light-for-dates 129 6 3.9 0.73 (0.29–1.86) 0.81 (0.31–2.08) 10 7.8 0.62 (0.32–1.21) 0.66 (0.33–1.30) 9 7.0 1.06 (0.52–2.17) 1.15 (0.55–2.40)
Appropriate/heavy-for-dates 1073 56 5.2 1.00 1.00 128 11.9 1.00 1.00 71 6.6 1.00 1.00
High catch-up in weight
High catch-up 120 7 5.8 1.18 (0.52–2.65) 1.25 (0.55–2.84) 15 12.5 1.11 (0.63–1.97) 1.09 (0.61–1.96) 7 6.8 0.86 (0.38–1.90) 0.83 (0.37–1.87)
Non high catch-up 1082 54 5.0 1.00 1.00 123 11.4 1.00 1.00 73 5.8 1.00 1.00

OR, odds ratio; 95% CI, 95% confidence interval. aA model incorporated sex, one of anthropometric characteristics (Birthweight < 2500 g/ >= 2500 g, birthweight < 2500 g/ 2500–4000 g/ > 4000 g, preterm born, light-for-dates, or high catch-up in weight), maternal and paternal asthma and allergic disease history, maternal educational level, number of siblings, living in urban area, and environmental tobacco smoke exposure.