Table II.
Genes with downregulated expression in MG63/VCR relative to MG63 cells.
| Gene | Gene name | P-value | Fold change | False discovery rate |
|---|---|---|---|---|
| Transcription factors | ||||
| TP63 | Tumor protein 63 | 0.00092 | −7.26360 | 0.00266 |
| ZEB2 | Zinc finger E-box binding homeobox 2 | 0.00016 | −4.23951 | 0.00145 |
| Transporters | ||||
| FABP5 | Fatty acid binding protein 5 (psoriasis-associated) | <0.00001 | −66.32220 | 0.00035 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | 0.00055 | −4.11858 | 0.00220 |
| Transmembrane receptors | ||||
| IL13RA2 | Interleukin 13 receptor, a2 | 0.00008 | −15.08010 | 0.00111 |
| Enzymes | ||||
| PLSCR4 | Phospholipase scramblase 2 | 0.00226 | −5.89258 | 0.00442 |
| CHI3L1 | Chitinase 3-like 1 (cartilage glycoprotein-39) | <0.00001 | −196.98900 | 0.00061 |
| TGM2 | Transglutaminase 2 | 0.00006 | −4.85356 | 0.00106 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | 0.00011 | −5.37078 | 0.00124 |
| MSMO1 | Methylsterol monooxygenase 1 | 0.00232 | −8.35006 | 0.00449 |
| LOX | Lysyl oxidase | 0.00035 | −4.77463 | 0.00180 |
| AKR1C3 | Aldo-keto reductase family 1, member C3 | 0.00009 | −6.83914 | 0.00116 |
| Other | ||||
| IL15 | Interleukin 15 | 0.00427 | −4.77006 | 0.00698 |
| CCL2 | Chemokine (C-C motif) ligand 2 | 0.00107 | −7.26246 | 0.00288 |
| KCNK2 | Potassium channel, two pore domain subfamily K, member 2 | 0.00017 | −5.20959 | 0.00146 |
| KCNJ2 | Potassium channel, inwardly rectifying subfamily J, member 2 | 0.00017 | −4.15907 | 0.00146 |
| DAPK1 | Death-associated protein kinase 1 | 0.00072 | −5.37922 | 0.00242 |
| DKK1 | Dickkopf WNT signaling pathway inhibitor 1 | 0.00007 | −6.61779 | 0.00109 |
| GSAP | γ-secretase activating protein | 0.00104 | −4.12709 | 0.00283 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | <0.00001 | −4.76113 | 0.00058 |
| SLIT2 | Slit guidance ligand 2 | 0.00037 | −8.33081 | 0.00186 |
| THBS2 | Thrombospondin 2 | <0.00001 | −4.12890 | 0.00047 |
| CCDC102B | Coiled-coil domain containing 102B | 0.00063 | −6.34919 | 0.00230 |
| CDH2 | Cadherin 2, type 1, N-cadherin (neuronal) | <0.00001 | −8.36960 | 0.00045 |
| TM4SF18 | Transmembrane 4 L six family member 18 | 0.00016 | −6.42868 | 0.00145 |
| FLRT3 | Fibronectin leucine rich transmembrane protein 3 | 0.00057 | −5.87903 | 0.00224 |
| THY1 | Thy-1 cell surface antigen | <0.00001 | −18.64350 | 0.00046 |
| SHISA3 | Shisa family member 3 | <0.00001 | −8.51613 | 0.00035 |
| ITGB8 | Integrin, b8 | 0.00578 | −4.32276 | 0.00873 |
| CDH11 | Cadherin 11, type 2, OB-cadherin (osteoblast) | 0.00001 | −8.02862 | 0.00065 |
| COL3A1 | Collagen, type III, a1 | 0.00011 | −11.94630 | 0.00124 |
| PCDH18 | Protocadherin 18 | 0.00109 | −4.42683 | 0.00290 |
| LRCH2 | Leucine-rich repeats and calponin homology (CH) domain containing 2 | 0.00129 | −5.18966 | 0.00321 |
| SEMA6D | Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D | 0.00004 | −4.88122 | 0.00096 |
| TES | Testin LIM domain protein | 0.00015 | −22.05530 | 0.00139 |
| LUM | Lumican | 0.00582 | −4.02085 | 0.00877 |
| SPRY1 | Sprouty RTK signaling antagonist 1 | 0.00009 | −6.06186 | 0.00116 |
| Other | ||||
| CD46 | CD46 molecule, complement regulatory protein | 0.01614 | −4.36522 | 0.01969 |
| CCNG1 | Cyclin G1 | 0.00188 | −6.89583 | 0.00396 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.00005 | −6.61567 | 0.00106 |
| FLRT2 | Fibronectin leucine rich transmembrane protein 2 | 0.00004 | −4.43384 | 0.00098 |
| SNTB1 | Syntrophin, b1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.00068 | −4.41392 | 0.00236 |
| AIF1L | Allograft inflammatory factor 1-like | 0.00014 | −8.21928 | 0.00138 |
| GAL | Galanin/GMAP prepropeptide | <0.00001 | −11.35750 | 0.00051 |
| VCAN | Versican | 0.00019 | −12.17840 | 0.00152 |