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. 2018 Dec 17;19(3):1463–1470. doi: 10.3892/mmr.2018.9773

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Copyright: © Sun et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Expression of miR-495 is downregulated in NSCLC tissues and cells. (A) Reverse transcription-quantitative polymerase chain reaction was used to detect the expression levels of miR-145 in NSCLC and paracarcinoma tissues. The expression of miR-495 was significantly downregulated in NSCLC tissues compared with matched paracarcinoma tissues. ***P<0.001 vs. paracarcinoma tissues. (B) Expression levels of miR-495 were also reduced in NSCLC cell lines A549, H460, H1650, H520 and SK-MES-1 compared with the normal pulmonary bronchial epithelial cell line 16HBE. ***P<0.001 vs. 16HBE cells. MiR, microRNA; NSCLC, non-small cell lung cancer.