Table 1.
Experimental data for juvenile elephant seals used in the RNAseq study, including cortisol and aldosterone concentrations measured immediately before and 4 hours following administration of ACTH (pre-ACTH and ACTH response, respectively; from McCormley et al.12).
| Subject | Sex | Mass (kg) | ACTH (U/kg) | Day | pre-ACTH cortisol (nM) | ACTH response cortisol (nM) | pre-ACTH aldosterone (pM) | ACTH response aldosterone (pM) |
|---|---|---|---|---|---|---|---|---|
| Seal 2 | M | 119 | 0.17 | 1 4 |
198.7 202.2 |
760.2 2626.1 |
812.6 1204.2 |
1465.8 2110.5 |
| Seal 4 | M | 125 | 0.16 | 1 4 |
429.1 227.7 |
1298.5 1704.1 |
828.4 1476.5 |
2000.1 2608.5 |
| Seal 6 | F | 103 | 0.19 | 1 4 |
357.9 494.3 |
1542.1 4454.3 |
670.9 1610.1 |
1251.1 2747.1 |
| Seal 7 | F | 99 | 0.20 | 1 4 |
394.6 355.5 |
2598.6 2319.2 |
792.2 1291.3 |
1415.0 2123.0 |
ACTH: adrenocorticotropic hormone.
Aldosterone responses to the fourth ACTH administration were significantly enhanced relative to the first (p < 0.05), while cortisol responses to the first and fourth ACTH administrations did not vary in magnitude12.