Table 1.

Differentially spliced or expressed genes for data sets analysed.

Type of alteration WT vs K700E	MDS6	NALM-64	This study (whole cell)
A3SS	187	262	405
A5SS	207	180	362
MXE	99	46	249
RI	937	323	580
SE	1385	834	2111
Total unique changes	2815	1421	2896
Up-regulated	156	72	1566
Down-regulated	132	89	1386

Numbers represent unique genes. Differential expression threshold - fold-change >2 & FDR < 0.05 A3SS/A5SS – alternative 3′/5′ splice site; MXE – Mutually exclusive exons; SE – Skipped exons; RI – Retained introns.