Table 3. Distribution of SNPs of ACAT-2 gene in CAD and controls.
| Genotype | Model | Case (n, %) | Control (n, %) | P | Crude OR (95% CI) | P | |
|---|---|---|---|---|---|---|---|
| rs28765985 | Codominant | TT | 396 (76.7) | 267 (84.0) | 0.027 | 1 | 0.031 |
| CT | 110 (21.3) | 49 (15.4) | 1.514 (1.045–2.193) | 0.028 | |||
| CC | 10 (1.9) | 2 (0.6) | 3.371 (0.733–15.508) | 0.119 | |||
| Dominant | TT | 396 (76.7) | 267 (84.0) | 0.012 | 1 | 0.013 | |
| CT+CC | 120 (23.3) | 51 (16.0) | 1.586 (1.104–2.280) | ||||
| Recessive | TT+CT | 506 (98.1) | 316 (99.4) | 0.123 | 1 | 0.143 | |
| CC | 10 (1.9) | 2 (0.6) | 3.123 (0.680–14.344) | ||||
| Overdominant | CC+TT | 406 (78.7) | 269 (84.6) | 0.035 | 1 | 0.036 | |
| CT | 110 (21.3) | 49 (15.4) | 1.487 (1.027–2.154) | ||||
| rs7308390 | Codominant | CC | 427 (82.8) | 269 (84.6) | 0.776 | 1 | 0.776 |
| CT | 81 (15.7) | 45 (14.2) | 1.134 (0.764–1.683) | 0.533 | |||
| TT | 8 (1.6) | 4 (1.3) | 1.260 (0.376–4.225) | 0.708 | |||
| Dominant | CC | 427 (82.8) | 269 (84.6) | 0.488 | 1 | 0.488 | |
| CT+TT | 89 (17.2) | 49 (15.4) | 1.144 (0.782–1.674) | ||||
| Recessive | CT+CC | 508 (98.4) | 314 (98.7) | 0.73 | 1 | 0.731 | |
| TT | 8 (1.6) | 4 (1.3) | 1.236 (0.369–4.139) | ||||
| Overdominant | CC+TT | 435 (84.3) | 273 (85.8) | 0.545 | 1 | 0.545 | |
| CT | 81 (15.7) | 45 (14.2) | 1.130 (0.761–1.676) |