Table 6. Stratified analysis between ACAT gene polymorphisms and CAD risk.
Case/control | rs28765985 (Genetype) | Adjusted OR (95% CI) | P value | rs7308390 (Genetype) | Adjusted OR (95% CI) | P value | |
---|---|---|---|---|---|---|---|
Gender | |||||||
Male | 361/210 | CT+CC/TT | 1.524 (0.963–2.413) | 0.072 | CT+TT/CC | 1.583 (0.987–2.540) | 0.057 |
Female | 155/108 | CT+CC/TT | 1.800 (0.878–3.689) | 0.108 | CT+TT/CC | 0.566 (0.243–1.318) | 0.187 |
Hypertension | |||||||
No | 260/195 | CT+CC/TT | 1.538 (0.939–2.520) | 0.088 | CT+TT/CC | 1.360 (0.798–2.317) | 0.59 |
Yes | 256/123 | CT+CC/TT | 1.546 (0.844–2.829) | 0.158 | CT+TT/CC | 1.078 (0.588–1.979) | 0.807 |
Smoking | |||||||
No | 350/233 | CT+CC/TT | 1.342 (0.863–2.086) | 0.192 | CT+TT/CC | 0.914 (0.555–1.506) | 0.725 |
Yes | 166/85 | CT+CC/TT | 2.406 (1.057–5.479) | 0.036 | CT+TT/CC | 2.027 (0.997–4.121) | 0.051 |
Drinking | |||||||
No | 412/263 | CT+CC/TT | 1.364 (0.904–2.057) | 0.139 | CT+TT/CC | 1.012 (0.645–1.588) | 0.96 |
Yes | 104/55 | CT+CC/TT | 3.171 (1.064–9.445) | 0.038 | CT+TT/CC | 1.897 (0.793–4.539) | 0.15 |