Table 1.
Variables | Non-CPPa (n=966), mean (SD) | CPP (n=791), mean (SD) | P valueb |
Age (years) | 7.07 (1.11) | 7.52 (0.99) | <.001 |
LHc (IU/L) | 0.12 (0.23) | 0.93 (1.28) | <.001 |
FSHd (IU/L) | 1.82 (1.30) | 3.01 (1.62) | <.001 |
GHe (ng/mL) | 3.27 (3.26) | 4.75 (4.69) | <.001 |
IGF-If (ng/mL) | 231.35 (65.93) | 317.87 (89.84) | <.001 |
IGFBP-3g (μg/mL) | 4.55 (0.52) | 4.81 (0.55) | <.001 |
Estradiol (pmol/L) | 102.56 (50.96) | 125.81 (60.97) | <.001 |
Prolactin (ng/mL) | 8.73 (5.39) | 8.59 (5.61) | .52 |
Testosterone (nmol/L) | 0.80 (0.39) | 0.94 (0.49) | <.001 |
Historyh (months) | 7.67 (10.39) | 9.27 (9.63) | <.001 |
Menstruation/menarche (yes, no) | N/Ai | N/A | .03 |
Heightj (cm) | 127.16 (8.61) | 131.61 (8.42) | <.001 |
Weightj (kg) | 27.32 (5.32) | 29.60 (4.95) | <.001 |
BMIk (kg/m2) | 16.73 (2.30) | 16.91 (1.96) | .34 |
Breast core (yes, no) | N/A | N/A | .02 |
Pubesl (1-5) | 1.06 (0.27) | 1.14 (0.44) | <.001 |
Pigmentation (yes, no) | N/A | N/A | .87 |
Left breastl (1-5) | 2.33 (0.84) | 2.76 (0.92) | <.001 |
Right breastl (1-5) | 2.32 (0.84) | 2.78 (0.92) | <.001 |
aCPP: central precocious puberty.
bThe equality of each indicator was evaluated by Chi-square or Student t test. P<.05 was considered significant.
cLH: luteinizing hormone.
dFSH: follicle-stimulation hormone.
eGH: growth hormone.
fIGF-I: insulin-like growth factor-I.
gIGFBP-3: insulin-like growth factor binding protein-3.
hAbnormal duration in records.
iN/A: not applicable.
jAt stimulation test.
kBMI: body mass index.
lTanner stage.