Table 5.

Classification of phospholipid species based on the number of double bonds (degree of fatty acid saturation) in the cortex of repetitive mTBI mice.

Significant changes in PC, SM, PE, and PI species with ‘0’, ‘1’ or ‘3 or more’ double bonds in the cortex of repetitive mTBI mice. Sample size for all groups across all time points is n = 4. All data represents mean μM per (10 mg) wet weight ± SEM. Individual molecular lipid species were quantified by LC/MS and were summed after LipidomeDB analyses to generate degree of fatty acid classification for each phospholipid species. Blue color code indicates an increase in lipid species, while a red color code indicates a decrease in lipid species. Asterisks represents ^∗P < 0.05 (lightest shade of blue or red); ^∗∗P < 0.01 (middle shade of blue or red); ^∗∗∗P < 0.001 (darkest shade of blue or red) for comparisons between r-mTBI/sham mice. PE, Phosphatidylethanolamine; LPE, Lysophosphatidylethanolamine; PC, Phosphatidylcholine; LPC, Lysophosphatidylcholine; PI, Phosphatidylinositol; SM, Sphingomyelin.