Table 3.
Predicted targets of baicalein.
| Protein name | Gene symbol |
|---|---|
| Prostaglandin G/H synthase 1 | PTGS1 |
| Androgen receptor | AR |
| Prostaglandin G/H synthase 2 | PTGS2 |
| Heat shock protein HSP 90 | HSP90AA1 |
| Heat shock protein HSP 90 | HSP90AB1 |
| mRNA of PKA Catalytic Subunit C-alpha | PRKACA |
| Dipeptidyl peptidase IV | DPP4 |
| Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, gamma isoform | PIK3CG |
| CGMP-inhibited 3′,5′-cyclic phosphodiesterase A | PDE3A |
| Trypsin-1 | PRSS1 |
| Nuclear receptor coactivator 2 | NCOA2 |
| Nuclear receptor coactivator 1 | NCOA1 |
| Calmodulin | CALM1 |
| Transcription factor p65 | RELA |
| RAC-alpha serine/threonine-protein kinase | AKT1 |
| Vascular endothelial growth factor A | VEGFA |
| Apoptosis regulator Bcl-2 | BCL2 |
| Proto-oncogene c-Fos | FOS |
| Apoptosis regulator BAX | BAX |
| Matrix metalloproteinase-9 | MMP9 |
| Caspase-3 | CASP3 |
| Cellular tumor antigen p53 | TP53 |
| Hypoxia-inducible factor 1-alpha | HIF1A |
| Fos-related antigen 1 | FOSL1 |
| Fos-related antigen 2 | FOSL2 |
| Cell division control protein 2 homolog | CDK1 |
| G2/mitotic-specific cyclin-B1 | CCNB1 |
| Myeloperoxidase | MPO |
| Aryl hydrocarbon receptor | AHR |
| Insulin-like growth factor II | IGF2 |
| Cytochrome c | CYCS |
| Arachidonate 12-lipoxygenase, 12S-type | ALOX12 |
| Nuclear factor of activated T-cells, cytoplasmic 1 | NFATC1 |
| Tudor domain-containing protein 7 | TDRD7 |
| Egl nine homolog 1 | EGLN1 |
| NADPH oxidase 5 | NOX5 |
| Fatty acid-binding protein, epidermal | FABP5 |
| Apolipoprotein D | APOD |