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. 2019 Feb 12;2019:7438593. doi: 10.1155/2019/7438593

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Copyright © 2019 Xiaoxi Liu et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Cytotoxicity of puerarin, baicalin, and berberine hydrochloride in IPEC-J2 cells. Treatment with puerarin at 200 μg/mL for 48 h did not significantly change the viability of IPEC-J2 cells (a). Treatment with baicalin at concentrations from 1 ng/mL to 1 μg/mL markedly promoted IPEC-J2 cell proliferation without causing cytotoxicity (b). At concentrations of 100 μg/mL or less berberine hydrochloride was found to be safe for treating IPEC-J2 cells for 48 h (c). Data are mean ± SEM, n = 6 per treatment (∗P < 0.05 versus control group; ∗∗P < 0.01 versus control group).