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. 2019 Feb 12;2019:8597159. doi: 10.1155/2019/8597159

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Copyright © 2019 Guang-Min Yu and Wen Tan.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Effect of melatonin on relative mRNA level of inflammatory cytokines and chemokines in LPS-stimulated mouse mammary tissue. (a) Effect of melatonin on relative mRNA level of TNF-α. (b) Effect of melatonin on relative mRNA level of IL-1β. (c) Effect of melatonin on relative mRNA level of IL-6. (d) Effect of melatonin on relative mRNA level of CXCL1. (e) Effect of melatonin on relative mRNA level of MCP-1. (f) Effect of melatonin on relative mRNA level of RANTES. Control: containing ethanol as the solvent at the same concentration used in the tests. LPS: a working concentration 100 ng/mL LPS. Mel: a working concentration 10 μg/mL melatonin. LPS+Mel: final concentrations of 100 ng/mL LPS and 10 μg/mL melatonin. Values with different letters differ significantly (P < 0.05).