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. 2019 Feb 26;19:45. doi: 10.1186/s12872-019-1023-5

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Representative optical coherence tomography images. a TCFA, defined as a lipid-rich plaque with a fibrous cap thickness < 65 μm (arrows). b Microvessels are represented by black holes within the plaque (arrow). c Cholesterol crystals are reflected by thin, linear regions of high intensity within the plaque (arrows). d Macrophage accumulation on OCT images, defined as increased signal intensity within the fibrous cap, accompanied by heterogeneous backward shadows (arrows). e Calcification is reflected by an area with low backscatter signal and a sharp border (arrows). f Plaque disruption showing discontinuity of the fibrous cap. g White (platelet-rich) thrombus is represented by low and homogeneous backscattering with low signal attenuation (arrow). h Red (red blood cell-rich) thrombus is represented by high backscattering with high attenuation (arrows)