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. 2019 Feb 26;9:6. doi: 10.1186/s13395-019-0190-5

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — T cell proliferation in response to osteopontin. BrdU incorporation in spleen cells (isolated from mice that received allografts) treated with vehicle, Con A or recombinant mouse osteopontin. WT, wild-type; KO, osteopontin-null. Data are expressed as absorbance at 450 nm and presented as mean ± s.e.m.; n = 3 animals from each group. Two-way ANOVA with Tukey’s multiple comparison test was used to compare values with the value for vehicle-treated (Veh) cells of the same genotype; ****p < 0.0001