Table 4.
Variables | 10 >Vitamin D ≥20 | 20 >Vitamin D >30 | ||||
---|---|---|---|---|---|---|
Intervention group (n=9) | Placebo group (n=9) | P | Intervention group (n=17) | Placebo group (n=16) | P | |
Anxiety | ||||||
Baseline | 12.89±3.14 | 11.11±5.16 | 0.06† | 12.00±4.82 | 11.12±5.51 | 0.63† |
16 weeks | 9.78±3.68 | 10.78±4.04 | 0.06† | 9.82±4.34 | 12.18±4.26 | 0.12† |
Change | -5±4.92 | 2.67±2.31 | 0.01†,** | -2.18±3.33 | 1.06±2.73 | 0.03†,** |
P (within group)‡ | 0.02 | 0.24 | 0.05 | 0.27 | ||
Stress | ||||||
Baseline | 13.22±4.23 | 12.77±2.63 | 0.79† | 13.29±6.02 | 14.44±4.98 | 0.33† |
16 weeks | 7.88±3.89 | 11.89±3.69 | 0.96† | 11.88±4.97 | 13.56±5.01 | 0.43† |
Change | -0.33±3.33 | -00±1.73 | 0.84† | 0.25 | 0.24 | 0.70† |
P (within group)‡ | 0.83 | 0.99 | -1.42±3.91 | -0.88±2.87 | ||
Depression | ||||||
Baseline | 12.77±4.14 | 9.22±4.15 | 0.46† | 11.40±5.22 | 13.18±5.06 | 0.33† |
16 weeks | 12.89±6.27 | 12.78±4.02 | 0.68† | 9.94±4.05 | 11.25±5.00 | 0.42† |
Change | -3.00±2.71 | -0.33±2.57 | 0.14† | -1.47±2.71 | 1.94±3.32 | 0.76† |
P (within group)‡ | 0.04 | 0.78 | 0.22 | 0.09 | ||
hs-CRP (mg/L) | ||||||
Baseline | 2.52 (1.19, 12.19) | 2.79 (1.54, 4.27) | 0.73₤ | 3.35 (1.80, 7.05) | 7.18 (2.71, 12.31) | 0.09₤ |
16 weeks | 2.21 (1.12, 9.09) | 2.56 (1.84, 5.51) | 0.07₤ | 2.56 (1.18, 7.88) | 6.01 (3.02, 11.89) | 0.04₤ |
Change | -0.75 (-1.82, -0.14) | 0.35 (-0.39, 0.86) | 0.01₤,** | -0.21 (-0.86, 0.27) | 0.23 (-1.51, 1.41) | 0.08₤ |
P (within group)¥ | 0.008** | 0.23 | 0.03 | 0.26 | ||
IL-10 (ng/mL) | ||||||
Baseline | 68.00 (48.70, 111.20) | 99.00 (59.30, 118.50) | 0.34₤ | 85.00 (62.50, 107.00) | 90.00 (74.12, 116.00) | 0.48₤ |
16 weeks | 92.00 (48.80, 143.25) | 83.00 (63.50, 114.50) | 0.76₤ | 94.00 (81.25, 164.50) | 83.50 (68.85, 109.25) | 0.26₤ |
Change | 4.40 (-6.35, 19.00) | 00.00 (-10.40, 6.20) | 0.34₤ | 10.00 (-3.25, 49.10) | 2.55 (-20.75, 14.76) | 0.08₤ |
P (within group)¥ | 0.31 | 0.67 | 0.67 | 0.83 |
Variables are represented mean±SD or median (25th, 75th percentiles). †By independent t-test, ‡By paired sample t-test, ¥Obtained from Wilcoxon signed rank test, ₤Obtained from Mann-Whitney test, **P<0.05. SD=Standard deviation, hs-CRP=high sensitivity C-reactive protein, IL-10=Interleukin 10