Fig. 1. General azide/alkyne scaffold construction of second-generation inhibitors via a ‘click’ reaction. The entire linker modality is a sulfinyl- or sulfonylphenyltriazole. NITVK locus = green; VXXLL locus = blue; yellow R = sulfinyl/sulfonyl.
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.