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. 2019 Jan 15;10(2):268–279. doi: 10.1039/c8md00405f

Table 2. Group I click products of azidophenylsulfoxides 10 and azidophenyl sulfones 13 with selected arylacetylenes 16–24.

Inline graphic
Compound Yield a (%)
28, R1 = Ph, R2 = 3-pyridyl, R3 = SO 46
29, R1 = Ph, R2 = 4-fluorophenyl, R3 = SO 86
30, R1 = Ph, R2 = 3-fluorophenyl, R3 = SO 97
31, R1 = Ph, R2 = 2-methoxyphenyl, R3 = SO 95
32, R1 = Ph, R2 = 2-(trifluoromethyl)phenyl, R3 = SO 60
33, R1 = Ph, R2 = 6-methoxynaphthalene-2-yl, R3 = SO 58
34, R1 = Ph, R2 = 4-(n-pentyl)phenyl, R3 = SO 39
35, R1 = Ph, R2 = 4-(phenoxy)phenyl, R3 = SO 79
36, R1 = Ph, R2 = 3,5-di-(trifluoromethyl)phenyl, R3 = SO 89
37, R1 = Ph, R2 = 3-pyridyl, R3 = SO2 73
38, R1 = Ph, R2 = 4-fluorophenyl, R3 = SO2 63
39, R1 = Ph, R2 = 3-fluorophenyl, R3 = SO2 69
40, R1 = Ph, R2 = 2-methoxyphenyl, R3 = SO2 98
41, R1 = Ph, R2 = 2-(trifluoromethyl)phenyl, R3 = SO2 54
42, R1 = Ph, R2 = 6-methoxynaphthalene-2-yl, R3 = SO2 97
43, R1 = Ph, R2 = 4-(n-pentyl)phenyl, R3 = SO2 77
44, R1 = Ph, R2 = 4-(phenoxy)phenyl, R3 = SO2 97
45, R1 = Ph, R2 = 3,5-di-(trifluoromethyl)phenyl, R3 = SO2 63

aYields are for isolated pure compounds.