Table 2. Group I click products of azidophenylsulfoxides 10 and azidophenyl sulfones 13 with selected arylacetylenes 16–24.
| |
Compound | Yield a (%) |
28, R1 = Ph, R2 = 3-pyridyl, R3 = SO | 46 |
29, R1 = Ph, R2 = 4-fluorophenyl, R3 = SO | 86 |
30, R1 = Ph, R2 = 3-fluorophenyl, R3 = SO | 97 |
31, R1 = Ph, R2 = 2-methoxyphenyl, R3 = SO | 95 |
32, R1 = Ph, R2 = 2-(trifluoromethyl)phenyl, R3 = SO | 60 |
33, R1 = Ph, R2 = 6-methoxynaphthalene-2-yl, R3 = SO | 58 |
34, R1 = Ph, R2 = 4-(n-pentyl)phenyl, R3 = SO | 39 |
35, R1 = Ph, R2 = 4-(phenoxy)phenyl, R3 = SO | 79 |
36, R1 = Ph, R2 = 3,5-di-(trifluoromethyl)phenyl, R3 = SO | 89 |
37, R1 = Ph, R2 = 3-pyridyl, R3 = SO2 | 73 |
38, R1 = Ph, R2 = 4-fluorophenyl, R3 = SO2 | 63 |
39, R1 = Ph, R2 = 3-fluorophenyl, R3 = SO2 | 69 |
40, R1 = Ph, R2 = 2-methoxyphenyl, R3 = SO2 | 98 |
41, R1 = Ph, R2 = 2-(trifluoromethyl)phenyl, R3 = SO2 | 54 |
42, R1 = Ph, R2 = 6-methoxynaphthalene-2-yl, R3 = SO2 | 97 |
43, R1 = Ph, R2 = 4-(n-pentyl)phenyl, R3 = SO2 | 77 |
44, R1 = Ph, R2 = 4-(phenoxy)phenyl, R3 = SO2 | 97 |
45, R1 = Ph, R2 = 3,5-di-(trifluoromethyl)phenyl, R3 = SO2 | 63 |
aYields are for isolated pure compounds.