Table 5. IC50 values for Group I compounds (28–45), Group II compounds (46–57) and Group III compounds (90–124).
Group I | IC50 a (μM) | Group II | IC50 a (μM) | Group III | IC50 a (μM) |
28 | NA | 46 | 5.30 | 90 | 20.7 |
29 | NA | 47 | 35.9 | 91 | NA |
30 | 47.3 | 48 | 7.20 | 92 | NA |
31 | NA | 49 | 15.1 | 93 | 9.4 |
32 | NA | 50 | 39.8 | 94 | 16.0 |
33 | NA | 51 | 10.2 | 95 | 3.7 |
34 | NA | 52 | 40.0 | 96 | NA |
35 | NA | 53 | 40.0 | 97 | 36.6 |
36 | NA | 54 | 21.2 | 98 | NA |
37 | NA | 55 | 18.2 | 99 | NA |
38 | 15.7 | 56 | 6.3 | 100 | 9.6 |
39 | 33.6 | 57 | 20.0 | 101 | NA |
40 | 13.1 | 102 | 5.00 | ||
41 | NA | 103 | 12.3 | ||
42 | NA | 104 | 33.8 | ||
43 | 36.6 | 105 | NA | ||
44 | 16.5 | 106 | NA | ||
45 | 38.5 | 107 | 40.0 | ||
108 | NA | ||||
109 | NA | ||||
110 | NA | ||||
111 | 4.3 | ||||
112 | NA | ||||
113 | 49.2 | ||||
114 | NA | ||||
115 | 2.3 | ||||
116 | >40.0 | ||||
117 | 27.8 | ||||
118 | 13.3 | ||||
119 | NA | ||||
120 | NA | ||||
121 | NA | ||||
122 | 2.4 | ||||
123 | 8.00 | ||||
124 | 7.8 |
aNA = not active.