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. 2019 Feb 19;10:116. doi: 10.3389/fphys.2019.00116

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Copyright © 2019 Satti, Abid, Bottaro, De Rui, Garrido, Raoufy, Montagnese and Mani.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Pearson’s r from the extended Poincaré plot demonstrates the relationship between R-R_n and R-R_n ₊ _k (k_max = 20) in healthy volunteers and patients with liver cirrhosis from the least severe (Child A), moderate (Child B) and in the most severe cases (Child C). (B) The SD1 calculated in the extended Poincaré plot is shown. (C) The SD2 calculated in the extended Poincaré plot is shown.