Table 2. Inhibitory effects and IC₅₀ of peptide binding rrNRP-1 (colorimetric detection) ^e .

Compound	AA2–AA3 fragment	Inhibition of NRP-1/VEGF-A165 binding [%]					IC50 [μM]
		10 μM	3 μM	1 μM	0.3 μM	0.1 μM
1	n/a	61.0 ± 0.4	38.1 ± 3.7	24.4 ± 3.5	14.6 ± 2.3	2.9 ± 2.1	5.9 ± 0.7 a
2	Pro–Pro	92.2 ± 0.8	79.0 ± 1.5	41.4 ± 0.0	4.7 ± 0.1	—	1.0 ± 0.3 b
3	Dab–Pro	99.6 ± 0.3	92.8 ± 1.1	83.7 ± 0.2	59.6 ± 0.1	35.8 ± 3.2	0.2 ± 0.4 c
4	Pro–Ala	94.4 ± 0.4	89.4 ± 0.8	77.5 ± 0.1	54.2 ± 0.3	26.3 ± 2.1	0.3 ± 0.1 d

^alog IC₅₀ = –5.23 ± 0.07.

^blog IC₅₀ = –5.99 ± 0.06.

^clog IC₅₀ = –6.70 ± 0.05.

^dlog IC₅₀ = –6.53 ± 0.05; R² ranged between 0.98–0.99. Results are presented as the mean ± SEM. n/a means not applicable.

^eA part of data was already published.40