Table 1. Summary of the dissolution data from the various samples and the modeling according to eqn (1) and (2) with Mmax being the estimated maximum release, ker being the effective release constant, R2 being the coefficient of determination for the fit with model 1 and n being the exponent of the fits using eqn (2).
Material | Coating | T [°C] | M max [%/100] | k er [103 min–1] | R 2 | n (Kors. Peppa) |
Phen | – | 25 | 1.00 | 1.37 | 0.97 | 0.877 |
– | 37 | 1.00 | 3.64 | 0.99 | 0.948 | |
+ | 25 | 0.43 | 0.18 | 0.99 | 1.348 | |
+ | 37 | 0.71 | 3.09 | 0.97 | 1.063 | |
Clot | – | 25 | 1.00 | 10.42 | 0.98 | 0.828 |
– | 37 | 1.00 | 20.41 | 0.99 | 0.950 | |
+ | 25 | 0.12 | 0.79 | 1.00 | 0.471 | |
+ | 37 | 0.38 | 4.88 | 1.00 | 1.386 | |
Indo | – | 25 | 1.00 | 9.35 | 0.97 | 0.870 |
– | 37 | 1.00 | 20.43 | 0.98 | 0.853 | |
+ | 25 | 0.25 | 2.07 | 1.00 | 1.067 | |
+ | 37 | 0.59 | 3.79 | 1.00 | 1.108 | |
Indo pH 7 | – | 25 | Burst release | |||
– | 37 | Burst release | ||||
+ | 25 | 0.73 | 24.40 | 0.99 | 0.685 | |
+ | 37 | 0.28 | 99.05 | 0.97 | 0.717 |