Table 1. Deprotection condition screening.

Entry	Conditions	Time/h	Conversion a /%
1	KI (2 equiv.)	24	—
2	KBr (2 equiv.)	24	—
3	KCl (2 equiv.)	24	—
4	KF (2 equiv.)	24	<1
5	KI (2 equiv.), 18-C-6 (3 equiv.)	24	<1
6	KF (2 equiv.), 18-C-6 (3 equiv.)	24	1
7	NaI (2 equiv.), 18-C-6 (3 equiv.)	24	<1
8	KF (2 equiv.), 18-C-6 (3 equiv.), methyl thioglycolate (10 equiv.)	1	78
9	KF (2 equiv.), methyl thioglycolate (10 equiv.)	1	61
10	KF (1 equiv.), 18-C-6 (1 equiv.), methyl thioglycolate (2 equiv.)	1	57
11	Methyl thioglycolate (10 equiv.)	24	<1
12	Methyl thioglycolate (10 equiv.). K2CO3 (2 equiv.)	24	90

^aConversion was determined by ¹H NMR analysis of the reaction mixture (see ESI). All reactions were carried out in a water bath set to 50 °C.